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Given the potential for the evolution of SARS-CoV-2 variants that render vaccines less effective (vaccine escape), assisted by waning immunity following vaccination, how can COVID-19 exit strategies be planned while limiting the vaccine escape risk?
A key component of any plausible strategy towards the permanent removal of non-pharmaceutical interventions (NPIs) is ensuring low case numbers in the short to medium term using NPIs and vaccination.
Read this paper which discusses this mathematically
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00202-4/fulltext
